Metropolis (1949), one third of Osamu Tezuka's early "science-fiction trilogy", was originally published as a stand-alone, book-length adventure by Ikuei Publishing on September 15, 1949.
New Treasure Island (1947) is, by and large, considered Osamu Tezuka's debut work. It was first published in January 1947, when Tezuka was still a 19 year-old medical student, and although it was preceded by the "gag manga" strip, The Diary of Ma-chan (1946), it is Tezuka's first long-form "story manga".
Types of Tezuka Manga
Ongoing Serial: a series of episodes, published over a span of weeks/months/years where the story plot is connected from chapter to chapter and must be read in chronological order for it to be understood properly.
Chapter Serial: a series of episodes, published over a span of weeks/months/years where the story plot is self-contained to a single chapter. There may be an overarching plot, but the stories can generally be read in any order and be understood
Book: an all-in-one self contained story published as a one-off.
Supplement: an an all-in-one self contained story published as a stand-alone supplement to a regular weekly/monthly periodical.
Short Story: an all-in-one, self contained story that was published in a regular weekly/monthly periodical
Anthology: a collection of all-in-one, self contained stories that were published in a regular weekly/monthly periodical but are generally grouped together.