Melmo
Melmo was the trailblazer of the "magical girl" genre, and pioneered the transformation sequence. Orphaned at a young age, Melmo's dead mother begs God for help for her daughter. God decides to grant her wish and bestows upon young Melmo a bottle of magical candy - with the blue ones physically making her grow older, and the red ones making her grow younger, all the while maintaining the innocent mind of a 9-year-old.